Establishment and characterization of a simian virus 40-transformed temperature-sensitive rat luteal cell line.

@article{Sugino1998EstablishmentAC,
  title={Establishment and characterization of a simian virus 40-transformed temperature-sensitive rat luteal cell line.},
  author={N Sugino and Mirjam Zilberstein and R. K. Srivastava and Carlos M. Telleria and Scott Edward Nelson and Michael Risk and Janice Y Chou and Geula Gibori},
  journal={Endocrinology},
  year={1998},
  volume={139 4},
  pages={1936-42}
}
The primary culture of rat luteal cells and their long-term maintenance have been difficult. Low cellular yields have limited the possibility for the study of gene regulation in luteal cells. The goal of this study was to develop a cell line to serve as a model by which to study the expression and regulation of various genes specific to luteal cells. We attempted to develop a luteal cell line by transformation of large luteal cells through infection with a temperature-sensitive simian virus (SV… CONTINUE READING
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