Establishment and characterization of a pair of non-malignant and malignant tumor derived cell lines from an African American prostate cancer patient.

@article{Theodore2010EstablishmentAC,
  title={Establishment and characterization of a pair of non-malignant and malignant tumor derived cell lines from an African American prostate cancer patient.},
  author={Shaniece C. Theodore and Starlette Sharp and Jianjun Zhou and Timothy Turner and Hongzhen Li and Jun Miki and Youngmi Ji and Vyomesh Patel and Clayton Yates and Johng S. Rhim},
  journal={International journal of oncology},
  year={2010},
  volume={37 6},
  pages={1477-82}
}
Research into molecular and genetic mechanisms underlying prostate carcinogenesis in high-risk African American men would be greatly advanced by in vitro models of African American prostate tumors representing primary tumors. However, the generation of immortalized primary African American prostate cancer cells that will accurately reflect the in situ characteristics of malignant epithelium is currently limited but is greatly needed. We have successfully established immortalized cell lines of a… CONTINUE READING
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