Establishment and characterization of a canine T-lymphoblastoid cell line derived from malignant lymphoma.

@article{Momoi1997EstablishmentAC,
  title={Establishment and characterization of a canine T-lymphoblastoid cell line derived from malignant lymphoma.},
  author={Yasuyuki Momoi and Yasuji Okai and Toshihiro Watari and Ryo Goitsuka and Hajime Tsujimoto and Atsuhiko Hasegawa},
  journal={Veterinary immunology and immunopathology},
  year={1997},
  volume={59 1-2},
  pages={11-20}
}
A canine lymphoma cell line (CL-1) was established in culture from tumor cells found in the pleural fluid of a 7-year old female Japanese terrier with thymic form lymphoma. The CL-1 cells were positive for CD45 and MHC class II and negative for CD4, CD5, CD8, Thy-1 and B-cell specific antigen and surface immunoglobulin. The CL-1 cells had a rearranged T-cell receptor beta-chain gene and a germ-line form immunoglobulin gene, indicating that the CL-1 cells represented a monoclonally expanded… CONTINUE READING

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