Establishment and characterization of 20 human non-small cell lung cancer cell lines in a serum-free defined medium (ACL-4).

@article{Masuda1991EstablishmentAC,
  title={Establishment and characterization of 20 human non-small cell lung cancer cell lines in a serum-free defined medium (ACL-4).},
  author={Norikazu Masuda and Masahiro Fukuoka and Minoru Takada and Shoji Kudoh and Yasuo Kusunoki},
  journal={Chest},
  year={1991},
  volume={100 2},
  pages={429-38}
}
To facilitate the studies in cell biology and drug sensitivity of non-small cell lung cancer, cell samples from 55 patients have been used to establish cell lines in culture using a chemically defined medium (ACL-4). A total of 20 cell lines (36 percent) were directly established and characterized: 14 (44 percent) from pleural effusions, five (29 percent) from resected primary tumors, and one (25 percent) from ascitic fluids. They comprised 16 adenocarcinoma, two large cell carcinoma, one… CONTINUE READING

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