Establishment and Characterization of a New Spontaneous Metastasis Model of Human Gastric Carcinoma in Nude Mice

@inproceedings{Nakanishi1991EstablishmentAC,
  title={Establishment and Characterization of a New Spontaneous Metastasis Model of Human Gastric Carcinoma in Nude Mice},
  author={Hayao Nakanishi and Kenzo Yasui and Sadako Yamagata and Satoru Shimizu and Shoji Ando and Syun Hosoda},
  booktitle={Japanese journal of cancer research : Gann},
  year={1991}
}
A poorly differentiated medullary carcinoma of human stomach, designated HY-1, was successfully transplanted to nude mice by either the subcutaneous or intramuscular route for five generations. The transplanted tumor showed spontaneous lung metastases in nearly 100% of KSN and Balb/c female nude mice. There were over 20 visible lung metastatic nodules in… CONTINUE READING