Establishment, characterization, and response to cytotoxic and radiation treatment of three human melanoma cell lines

Abstract

Three human melanoma cell lines were derived from tumor specimens and established in culture. CAL 1 originated from a bone marrow metastasis and CAL 4 and CAL 7 were derived from solid tumor fragments. CAL 1 and CAL 7 were cloned before establishment. Ultrastructural and chromosome analysis were carried out along with the response to nine chemotherapeutic… (More)
DOI: 10.1007/BF02619592

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