[Establishing the structure of anthracyclinones produced by Streptomyces griseoruber].

Abstract

Streptomyces grisoruber strain 1618-306 produces three types of anthracycline antibiotics, derivatives of epsilon-pyrromycinone (methyl (7S, 9R, 10R)-9-ethyl-5,7,8,9,10,12-hexahydro-1,4,6,7,9-pentahydroxy-5,12-di oxo-10- naphthacenecarboxylate), epsilon-1-hydroxyauramycinone and epsilon-1-hydroxysulfurmycinone, differing in C-9 substituent in D ring of anthracyclines (Et, Met or CH2COCH3, respectively). Besides 7-O-glycosides of these aglycones, complex of antibiotics contains corresponding 7-deoxy- and 7,8,9,10-bisanhydroanthracyclinones.

Cite this paper

@article{Bakina1989EstablishingTS, title={[Establishing the structure of anthracyclinones produced by Streptomyces griseoruber].}, author={E V Bakina and I V Iartseva and L. S. Povarov and L. G. Aleksandrova and K A Tulemisova and L P Mamonova and M N Preobrazhenskaia}, journal={Bioorganicheskaia khimiia}, year={1989}, volume={15 10}, pages={1423-30} }