Establishing individual metabolite patterns for patients on valproate therapy


The aim of this study was to establish individual metabolic profiles of patients receiving valproate (VPA) mono- or polytherapy in order to estimate inter- and intraindividual variability under normal conditions. Serum levels of VPA and 15 metabolites were measured by gas chromotography/mass spectrometry (GC/MS) with selected ion monitoring (SIM). Because… (More)
DOI: 10.1007/BF03190383


7 Figures and Tables