Establishing Good Practices for Exposure–Response Analysis of Clinical Endpoints in Drug Development

  title={Establishing Good Practices for Exposure–Response Analysis of Clinical Endpoints in Drug Development},
  author={RV Overgaard and S H Ingwersen and CW Torn\oe},
  booktitle={CPT: pharmacometrics & systems pharmacology},
This tutorial aims at promoting good practices for exposure-response (E-R) analyses of clinical endpoints in drug development. The focus is on practical aspects of E-R analyses to assist modeling scientists with a process of performing such analyses in a consistent manner across individuals and projects and tailored to typical clinical drug development decisions. This includes general considerations for planning, conducting, and visualizing E-R analyses, and how these are linked to key… CONTINUE READING
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