Established and new treatments for hereditary angioedema: An update.

@article{Cicardi2007EstablishedAN,
  title={Established and new treatments for hereditary angioedema: An update.},
  author={Marco Cicardi and Lorenza Chiara Zingale and Andrea Zanichelli and Daniela Lambertenghi Deliliers},
  journal={Molecular immunology},
  year={2007},
  volume={44 16},
  pages={3858-61}
}
Hereditary angioedema (HAE) is due to inherited deficiency of C1-inhibitor (C1-INH) and causes localized swelling that may be life-threatening when it affects the larynx. Replacement therapy with plasma derived C1-INH has been the principal life saving treatment for more than 20 years in several European countries. Nevertheless, it is not licensed in U.S. and even in Europe it is mostly supplied on a named patient basis. In the last 5 years, controlled clinical trials with four products (plasma… CONTINUE READING