Est-2 and Est-3 polymorphisms in Culex pipiens L. from southern France in relation to organophosphate resistance

@article{Pasteur1981Est2AE,
  title={Est-2 and Est-3 polymorphisms in Culex pipiens L. from southern France in relation to organophosphate resistance},
  author={Nicole Pasteur and Gilbert Sin{\`e}gre and Andr{\'e} Gabinaud},
  journal={Biochemical Genetics},
  year={1981},
  volume={19},
  pages={499-508}
}
Est-2 and Est-3 linkage disequilibrium was investigated in 43 natural populations. An association between Est-2 0.64 and Est-3 A alleles (or its reverse, Est-3 Null and alleles other than Est-2 0.64) was not observed in 19 (1.2%) of the 1599 mosquitoes analyzed, whereas it should have been found in nearly 400 (25%) individuals if the two loci were in equilibrium. This observation is discussed in relation to organophosphate resistance and genetic distance of the two genes. 

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