Essentials for ATP synthesis by F1F0 ATP synthases.

  title={Essentials for ATP synthesis by F1F0 ATP synthases.},
  author={Christoph von Ballmoos and Alexander Wiedenmann and Peter Dimroth},
  journal={Annual review of biochemistry},
The majority of cellular energy in the form of adenosine triphosphate (ATP) is synthesized by the ubiquitous F(1)F(0) ATP synthase. Power for ATP synthesis derives from an electrochemical proton (or Na(+)) gradient, which drives rotation of membranous F(0) motor components. Efficient rotation not only requires a significant driving force (DeltamuH(+)), consisting of membrane potential (Deltapsi) and proton concentration gradient (DeltapH), but also a high proton concentration at the source P… CONTINUE READING
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