Essentiality and Toxicity in Copper Health Risk Assessment: Overview, Update and Regulatory Considerations

@article{Stern2010EssentialityAT,
  title={Essentiality and Toxicity in Copper Health Risk Assessment: Overview, Update and Regulatory Considerations},
  author={B. Stern},
  journal={Journal of Toxicology and Environmental Health, Part A},
  year={2010},
  volume={73},
  pages={114 - 127}
}
  • B. Stern
  • Published 2010
  • Medicine, Biology
  • Journal of Toxicology and Environmental Health, Part A
  • Copper (Cu), an essential element required as a cofactor and/or structural component of numerous metalloenzymes, is uniquely positioned as a case study for issues associated with the essential metals health risk assessment, because of its extensive database. Essential elements pose distinct challenges when establishing regulatory guidelines because too little as well as too much intake can produce adverse health consequences and the dose-response curve is roughly U-shaped. Thus, conventional… CONTINUE READING
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