Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.

@article{Kimura2007EssentialRO,
  title={Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.},
  author={Atsushi Kimura and Tsukasa Ohmori and Ryunosuke Ohkawa and Seiji Madoiwa and Jun Mimuro and Takashi Murakami and Eiji Kobayashi and Yuichi Hoshino and Yutaka Yatomi and Yoichi Sakata},
  journal={Stem cells},
  year={2007},
  volume={25 1},
  pages={115-24}
}
Neural stem/progenitor cells (NSPCs) migrate toward a damaged area of the central nervous system (CNS) for the purpose of limiting and/or repairing the damage. Although this migratory property of NSPCs could theoretically be exploited for cell-based therapeutics of CNS diseases, little is known of the mechanisms responsible for migratory responses of NSPCs. Here, we found that sphingosine 1-phosphate (Sph-1-P), a physiological lysophospholipid mediator, had a potent chemoattractant activity for… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 10 times over the past 90 days. VIEW TWEETS
61 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 61 extracted citations

Similar Papers

Loading similar papers…