Essential roles for the nuclear receptor coactivator Ncoa3 in pluripotency

Abstract

Embryonic stem cells (ESCs) are valuable tools for regenerative medicine, being capable of self-renewing in culture indefinitely while retaining their pluripotency, i.e., the ability to generate any cell of the adult organism. At the heart of these capabilities is a complex transcriptional network, which carefully guards an uncommitted state, yet permits… (More)
DOI: 10.4161/cc.23377

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