Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling.

@article{Zhao2004EssentialRO,
  title={Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling.},
  author={Qingwei Zhao and Minako Ishibashi and Ken-ichi Hiasa and Chunyan Tan and Akira Takeshita and Kensuke Egashira},
  journal={Hypertension},
  year={2004},
  volume={44 3},
  pages={264-70}
}
Angiotensin II (Ang II) upregulates vascular endothelial growth factor (VEGF) and activates vascular inflammation. However, the decisive role of VEGF in Ang II-induced vascular inflammation and remodeling has not been addressed. Ang II infusion to wild-type mice increased local expression of VEGF and its receptors in cells of aortic wall and plasma VEGF… CONTINUE READING