Essential role of the synaptic vesicle protein synapsin II in formalin-induced hyperalgesia and glutamate release in the spinal cord.

@article{Schmidtko2005EssentialRO,
  title={Essential role of the synaptic vesicle protein synapsin II in formalin-induced hyperalgesia and glutamate release in the spinal cord.},
  author={Achim Schmidtko and Domenico Del Turco and Ovidiu Coste and Corina Ehnert and Ellen Niederberger and Peter J. van Ruth and Thomas Deller and Gerd 7 Geisslinger and Irmgard Tegeder},
  journal={Pain},
  year={2005},
  volume={115 1-2},
  pages={171-81}
}
The synaptic vesicle protein synapsin II plays an important role in the regulation of neurotransmitter release and synaptic plasticity. Here, we investigated its involvement in the synaptic transmission of nociceptive signals in the spinal cord and the development of pain hypersensitivity. We show that synapsin II is predominantly expressed in terminals and… CONTINUE READING