Essential role of the posterior morphogen nanos for germline development in Drosophila

@article{Kobayashi1996EssentialRO,
  title={Essential role of the posterior morphogen nanos for germline development in Drosophila},
  author={Satoru Kobayashi and Masashi Yamada and Miho Asaoka and Tomiichiro Kitamura},
  journal={Nature},
  year={1996},
  volume={380},
  pages={708-711}
}
IN many animal groups, factors required for germline formation are localized in germ plasm1, a region of the egg cytoplasm. In Drosophila embryos, germ plasm is located in the posterior pole region and is inherited in pole cells, the germline progenitors. Transplantation experiments have demonstrated that germ plasm contains factors that can form germline2–4, and germ plasm also directs abdomen formation5. Genetic analysis has shown that a common mechanism directs the localization of the… CONTINUE READING
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