Essential role of the Vp2 and Vp3 DNA-binding domain in simian virus 40 morphogenesis.

@article{Dean1995EssentialRO,
  title={Essential role of the Vp2 and Vp3 DNA-binding domain in simian virus 40 morphogenesis.},
  author={David A. Dean and Peggy P. Li and Li Ming Lee and Harumi Kasamatsu},
  journal={Journal of virology},
  year={1995},
  volume={69 2},
  pages={1115-21}
}
Both a DNA-binding domain and a Vp1 interactive determinant have been mapped to the carboxy-terminal 40 residues of the simian virus 40 (SV40) minor capsid proteins, Vp2 and Vp3 (Vp2/3), with the last 13 residues being necessary for these activities. The role of this DNA-binding domain in SV40 morphogenesis and the ability to separate these two signals were… CONTINUE READING