Essential role of somatic and synaptic protein synthesis and axonal transport in long-term synapse-specific facilitation at distal sensorimotor connections in Aplysia.

Abstract

To investigate further the cellular mechanisms underlying long-term facilitation (LTF) and long-term synapse-specific facilitation (LTSSF), we studied the role of axonal transport and somatic and synaptic protein synthesis at proximal and distal synapses of Aplysia siphon sensory neurons (SNs). The long soma-synapse distances (2.5 to 3 cm) of the SN distal… (More)

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