Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis

@article{Chubanov2005EssentialRF,
  title={Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis},
  author={Vladimir Chubanov and Thomas Gudermann and Karl P. Schlingmann},
  journal={Pfl{\"u}gers Archiv},
  year={2005},
  volume={451},
  pages={228-234}
}
Magnesium is an important cofactor for many biological processes such as protein synthesis, nucleic acid stability and neuromuscular excitability. The extracellular magnesium concentration is regulated tightly by the extent of intestinal absorption and renal excretion. Despite their critical role in magnesium handling, the molecular mechanisms mediating transepithelial transport are still not understood completely. Recently, genetic studies in patients with primary hypomagnesaemia and secondary… Expand
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