Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration.

@article{Bisaillon2010EssentialRF,
  title={Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration.},
  author={Jonathan M. Bisaillon and Rajender K Motiani and Jos{\'e} C. Gonz{\'a}lez-Cobos and Marie Potier and Katharine E. Halligan and Wael F Alzawahra and Margarida Barroso and Harold A. Singer and David Jourd'heuil and Mohamed Trebak},
  journal={American journal of physiology. Cell physiology},
  year={2010},
  volume={298 5},
  pages={C993-1005}
}
We recently demonstrated that thapsigargin-induced passive store depletion activates Ca(2+) entry in vascular smooth muscle cells (VSMC) through stromal interaction molecule 1 (STIM1)/Orai1, independently of transient receptor potential canonical (TRPC) channels. However, under physiological stimulations, despite the ubiquitous depletion of inositol 1,4,5-trisphosphate-sensitive stores, many VSMC PLC-coupled agonists (e.g., vasopressin and endothelin) activate various store-independent Ca(2… CONTINUE READING
54 Citations
51 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 54 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Similar Papers

Loading similar papers…