Essential oil from Korean Chamaecyparis obtusa leaf ameliorates respiratory activity in Sprague-Dawley rats and exhibits protection from NF-κB-induced inflammation in WI38 fibroblast cells

  title={Essential oil from Korean Chamaecyparis obtusa leaf ameliorates respiratory activity in Sprague-Dawley rats and exhibits protection from NF-$\kappa$B-induced inflammation in WI38 fibroblast cells},
  author={Suchismita Raha and Seong Min Kim and Ho Jeong Lee and Sang Joon Lee and Jeong Doo Heo and Venu Venkatarame Gowda Saralamma and Sang Eun Ha and Eun Hee Kim and Sungyong Mun and Gon Sup Kim},
  journal={International Journal of Molecular Medicine},
  pages={393 - 403}
  • S. Raha, S. Kim, G. Kim
  • Published 31 October 2018
  • Biology
  • International Journal of Molecular Medicine
To date, Korean hinoki cypress (Chamaecyparis obtusa), has been widely used for household and commercial purposes. Although the medicinal efficacy of hinoki cypress essential oil has been observed, that of the essential oil-derived terpenes, which exhibit a mechanism that acts against lung inflammation, remains to be fully elucidated. The present study investigated the anti-inflammatory effect of hinoki cypress leaf extracted essential oil on lipopolysaccharide (LPS)-stimulated WI38 fibroblast… 

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