Essential oil from Korean Chamaecyparis obtusa leaf ameliorates respiratory activity in Sprague-Dawley rats and exhibits protection from NF-κB-induced inflammation in WI38 fibroblast cells

@article{Raha2019EssentialOF,
  title={Essential oil from Korean Chamaecyparis obtusa leaf ameliorates respiratory activity in Sprague-Dawley rats and exhibits protection from NF-$\kappa$B-induced inflammation in WI38 fibroblast cells},
  author={Suchismita Raha and Seong Min Kim and Ho Jeong Lee and Sang Joon Lee and Jeong Doo Heo and Venu Venkatarame Gowda Saralamma and Sang Eun Ha and Eun Hee Kim and Sungyong Mun and Gon Sup Kim},
  journal={International Journal of Molecular Medicine},
  year={2019},
  volume={43},
  pages={393 - 403}
}
  • S. Raha, S. Kim, G. Kim
  • Published 31 October 2018
  • Biology
  • International Journal of Molecular Medicine
To date, Korean hinoki cypress (Chamaecyparis obtusa), has been widely used for household and commercial purposes. Although the medicinal efficacy of hinoki cypress essential oil has been observed, that of the essential oil-derived terpenes, which exhibit a mechanism that acts against lung inflammation, remains to be fully elucidated. The present study investigated the anti-inflammatory effect of hinoki cypress leaf extracted essential oil on lipopolysaccharide (LPS)-stimulated WI38 fibroblast… 
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References

SHOWING 1-10 OF 51 REFERENCES
Anti-inflammatory effects of essential oils extracted from Chamaecyparis obtusa on murine models of inflammation and RAW 264.7 cells.
TLDR
The results suggest that EOCO may exert anti-inflammatory effects in vivo and in vitro, and that these effects may be associated with the inhibition of inflammatory mediators.
Anti-inflammatory effect of essential oil and its constituents from fingered citron (Citrus medica L. var. sarcodactylis) through blocking JNK, ERK and NF-κB signaling pathways in LPS-activated RAW 264.7 cells.
  • Kil-Nam Kim, Yeong-Jong Ko, T. Oda
  • Biology, Chemistry
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2013
Effects of Essential Oil from Hinoki Cypress, Chamaecyparis obtusa, on Physiology and Behavior of Flies
TLDR
Investigation of the effects of essential oil extracted from C. obtusa on the physiologies and behaviors of Drosophila melanogaster and Musca domestica suggests that it can be used as a ‘human-friendly’ alternative insect repellent.
Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema
TLDR
No significant differences among the three monoterpenes treatments were found, suggesting that the presence of hydroxyl group in the molecular structure of thymol and carvacrol do not play a central role in the anti-inflammatory effects.
Anti-Inflammatory Effects of Cumin Essential Oil by Blocking JNK, ERK, and NF-κB Signaling Pathways in LPS-Stimulated RAW 264.7 Cells
TLDR
Results suggested that cumin essential oil extracted from seeds exerted anti-inflammatory effects in LPS-stimulated RAW 264.7 cells via inhibition of NF-κB and mitogen-activated protein kinases ERK and JNK signaling; the chemical could be used as a source of anti- inflammatory agents as well as dietary complement for health promotion.
Anti-inflammatory activity of Ailanthus altissima in ovalbumin-induced lung inflammation.
TLDR
The results suggest that the anti-inflammation activity of A. altissima in OVA-induced lung inflammation may occur in part via the down regulation of T(H)2 cytokines and eotaxin transcripts as well as the inhibition of inflammatory mediators.
Phytoncide Extracted from Pinecone Decreases LPS-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells.
TLDR
Results suggest that phytoncide can decrease LPS-induced inflammation in MAC-T cells and reduce the severity of lipopolysaccharide-induced inflammatory responses.
Antioxidant activity of pomegranate juice reduces emphysematous changes and injury secondary to cigarette smoke in an animal model and human alveolar cells
TLDR
The expression of inflammatory mediators associated with CS exposure and the emphysematous changes noted with chronic CS exposure were reduced with PJ supplementation, and in vitro, PJ attenuated the damaging effects of CS extract on cultured human alveolar cells.
In Vitro and in Vivo Therapeutics of β-Thujaplicin on Lps-Induced Inflammation in Macrophages and Septic Shock in Mice
TLDR
In agreement with the in vitro study, β-thujaplicin was shown to be effective in vivo for inhibiting LPS-induced NO and TNF-α production and a significant decrease in mortality rate of mice suffering from septic shock was observed.
Composition and Two Activities of the Leaf Essential Oil ofLitsea acuminata (Blume) Kurata from Taiwan
TLDR
This study investigated the chemical composition, antimicrobial and anti-wood-decay fungal activities of the essential oil isolated from the fresh leaves of Litsea acuminata (Blume) Kurata from Taiwan, and found that the oil demonstrated excellent activity against four wood- decay-fungi species.
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