Essential nutrients: food or supplements? Where should the emphasis be?

@article{Lichtenstein2005EssentialNF,
  title={Essential nutrients: food or supplements? Where should the emphasis be?},
  author={Alice H. Lichtenstein and Robert M Russell},
  journal={JAMA},
  year={2005},
  volume={294 3},
  pages={
          351-8
        }
}
The consumption of adequate levels and proper balance of essential nutrients is critical for maintaining health. The identification, isolation, and purification of nutrients in the early 20th century raised the possibility that optimal health outcomes could be realized through nutrient supplementation. Recent attempts using this approach for cardiovascular disease and lung cancer have been disappointing, as demonstrated with vitamin E and beta carotene. Moreover, previously unrecognized risks… 
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