Essential mixed cryoglobulinemia without evidence for hepatitis B virus infection.

  title={Essential mixed cryoglobulinemia without evidence for hepatitis B virus infection.},
  author={J{\'o}zsef Popp and Jules L. Dienstag and Jack R Wands and Kurt J. Bloch},
  journal={Annals of internal medicine},
  volume={92 3},
Prompted by reports associating essential mixed cryoglobulinemia with hepatitis B, we tested for hepatitis B markers in serum and cryoprecipitates and searched for virus particles by electron microscopy in cryoprecipitates from 12 patients with essential mixed cryoglobulinemia and 22 control subjects with mixed cryoglobulinemia secondary to recognized disease processes. None of the patients with essential cryoglobulinemia had detectable serum hepatitis B surface antigen (HBsAg) or antibody… CONTINUE READING


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