Essential functional role of the polysaccharide intercellular adhesin of Staphylococcus epidermidis in hemagglutination.

@article{Mack1999EssentialFR,
  title={Essential functional role of the polysaccharide intercellular adhesin of Staphylococcus epidermidis in hemagglutination.},
  author={Dietrich Mack and J Riedewald and H. G. E. Rohde and Tim Magnus and Heinz Hubert Feucht and H A Elsner and Rainer Laufs and Mark E. Rupp},
  journal={Infection and immunity},
  year={1999},
  volume={67 2},
  pages={1004-8}
}
Hemagglutination of erythrocytes is a common property of Staphylococcus epidermidis strains, which is related to adherence and biofilm formation and may be essential for the pathogenesis of biomaterial-associated infections caused by S. epidermidis. In three independent biofilm-producing, hemagglutination-positive S. epidermidis isolates, interruption of the icaADBC operon essential for polysaccharide intercellular adhesin (PIA) synthesis by Tn917 insertions led to a hemagglutination-negative… CONTINUE READING
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Characterization of the N-acetylglucosaminyltransferase activity involved in the biosynthesis of the Staphylococcus epidermidis polysaccharide intercellular adhesin

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