Essential function of Wnt-4 for tubulogenesis in the Xenopus pronephric kidney.

@article{Saulnier2002EssentialFO,
  title={Essential function of Wnt-4 for tubulogenesis in the Xenopus pronephric kidney.},
  author={Didier M E Saulnier and Hedyeh Ghanbari and Andr{\'e} W. Br{\"a}ndli},
  journal={Developmental biology},
  year={2002},
  volume={248 1},
  pages={13-28}
}
In the vertebrate embryo, development of the excretory system is characterized by the successive formation of three distinct kidneys: the pronephros, mesonephros, and metanephros. While tubulogenesis in the metanephric kidney is critically dependent on the signaling molecule Wnt-4, it is unknown whether Wnt signaling is equally required for the formation of renal epithelia in the other embryonic kidney forms. We therefore investigated the expression of Wnt genes during the pronephric kidney… CONTINUE READING
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