Essential fatty acid uptake and metabolism in the developing rodent brain

@article{Pawlosky1996EssentialFA,
  title={Essential fatty acid uptake and metabolism in the developing rodent brain},
  author={Robert J. Pawlosky and Glenn Ward and Norman Salem},
  journal={Lipids},
  year={1996},
  volume={31},
  pages={S103-S107}
}
Studies were carried out to determine whether the brain takes up and metabolizes essential fatty acids during early postnatal development in rodents. Rats and mice were dosed with deuterium-labeled linoleic and linolenic acids either by intraperitoneal injection or by gavage. Animals were killed at different times thereafter, and organs were removed. Brains, livers, and blood were analyzed by gas chromatography— negative-ion-mass spectrometry for labeled fatty acids. To determine whether fatty… CONTINUE READING

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