Essential elements of the native glucoregulatory system, which, if appreciated, may help improve the function of glucose controllers in the intensive care unit setting.

@article{DeJournett2010EssentialEO,
  title={Essential elements of the native glucoregulatory system, which, if appreciated, may help improve the function of glucose controllers in the intensive care unit setting.},
  author={Leon DeJournett},
  journal={Journal of diabetes science and technology},
  year={2010},
  volume={4 1},
  pages={190-8}
}
  • Leon DeJournett
  • Published 2010 in Journal of diabetes science and technology
In 2001, Van den Berghe and colleagues were able to show that tight glucose control decreases morbidity and mortality rates in the intensive care unit (ICU) setting. Several large, prospective, randomized controlled trials have failed to confirm these results. All of these studies attempted tight glucose control using expert-designed algorithms to adjust the rate of intravenous insulin. Unfortunately, these studies each had high rates of hypoglycemia, a high percentage of glucose values outside… CONTINUE READING

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