Essential components of the mini-exon gene promoter in the trypanosomatid Leptomonas seymouri.

@article{Hartree1995EssentialCO,
  title={Essential components of the mini-exon gene promoter in the trypanosomatid Leptomonas seymouri.},
  author={Douglas Hartree and Vivian Bellofatto},
  journal={Molecular and biochemical parasitology},
  year={1995},
  volume={71 1},
  pages={27-39}
}
In members of the Trypanosomatidae family of parasitic protozoa, the mini-exon (MX) genes encode the mini-exon donor RNA (medRNA) that contributes a small, 39-nt exon to all pre-mRNAs during mRNA maturation. Previously we have shown that a single copy of a MX gene can be expressed continuously from a stable episome transfected into the monogenetic trypanosomatid Leptomonas seymouri. We now identify components of the MX gene promoter. A series of 10-bp block substitution mutations in a tagged MX… CONTINUE READING

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