Essential Synergy between Ca 2+ and Guanine Nucleotides in Exocytotic Secretion from Permeabilized Rat Mast Cells

  • W. Howel
  • Published 1987

Abstract

Rat mast cells, pretreated with metabolic inhibitors and permeabilized by streptolysin-O, secrete histamine when provided with Ca 2+ (buffered in the micromolar range) and nucleoside triphosphates. We have surveyed the ability of various exogenous nucleotides to support or inhibit secretion. The preferred rank order in support of secretion is ITP > XTP… (More)

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Cite this paper

@inproceedings{Howel1987EssentialSB, title={Essential Synergy between Ca 2+ and Guanine Nucleotides in Exocytotic Secretion from Permeabilized Rat Mast Cells}, author={W. Howel}, year={1987} }