Essential Role of IL-12 in Angiogenesis in Type 2 Diabetes.

Abstract

Recently, IL-12 emerged as a critical player in type 2 diabetes complications. We previously reported that ischemia-induced angiogenesis is compromised in type 2 diabetic mice. In this study, we determined that IL-12 disruption rescued angiogenesis and arteriogenesis in type 2 diabetic mice. To induce type 2 diabetes, wild-type (WT), p40IL-12-/- (p40… (More)
DOI: 10.1016/j.ajpath.2017.07.021

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