Essential Protein Discovery Based on Network Motif and Gene Ontology

Abstract

Essential proteins are indispensable to support cellular life and constitute a minimal set required for a living cell. Fast progress in high-throughput technologies and large amount of data enable to discover essential proteins in system level by analyzing protein-protein interaction networks. A number of centrality algorithms are suggested to detect… (More)
DOI: 10.1109/BIBM.2011.46

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