Essential Oils and Anxiolytic Aromatherapy

  title={Essential Oils and Anxiolytic Aromatherapy},
  author={William N. Setzer},
  journal={Natural Product Communications},
  • W. Setzer
  • Published 1 September 2009
  • Biology, Medicine
  • Natural Product Communications
A number of essential oils are currently in use as aromatherapy agents to relieve anxiety, stress, and depression. Popular anxiolytic oils include lavender (Lavandula angustifolia), rose (Rosa damascena), orange (Citrus sinensis), bergamot (Citrus aurantium), lemon (Citrus limon), sandalwood (Santalum album), clary sage (Salvia sclarea), Roman chamomile (Anthemis nobilis), and rose-scented geranium (Pelargonium spp.). This review discusses the chemical constituents and CNS effects of these… 
Essential oil therapy helps in the treatment of epilepsy, stress, dementia by giving calming and soothing effects to the nerve cells and is also effective against dementia and on thetreatment of Alzheimer’s disease.
Naturally occurring anxiolytic substances from aromatic plants of genus citrus
The principal evidence in the literature about the use of essential oils of genus citrus with anxiolytic effects in preclinical models and clinical studies of anxiety is described.
Exploring Pharmacological Mechanisms of Lavender (Lavandula angustifolia) Essential Oil on Central Nervous System Targets
Evaluating the effects of lavender essential oil on central nervous system well-established targets, such as MAO-A, SERT, GABAAand NMDA receptors as well as in vitro models of neurotoxicity suggested that lavenderessential oil may exert pharmacological properties via modulating the NMDA receptor, the SERT aswell as neurotoxicity induced by hydrogen peroxide.
Review on Lemon Balm Herb and its Evaluation
Evaluated phytochemical screening of ethanolic extract of Melissa officinalis L. elicited a significant dose-dependent reduction in both inhibitory and excitatory transmission, which may help to find novel therapeutic agents in the treatment of anxiety.
Effects of Bergamot (Citrus bergamia (Risso) Wright & Arn.) Essential Oil Aromatherapy on Mood States, Parasympathetic Nervous System Activity, and Salivary Cortisol Levels in 41 Healthy Females
These results demonstrate that BEO inhaled together with water vapor exerts psychological and physiological effects in a relatively short time.
Aromatherapy in mental health: A brief review
Evidence for and against the use of aromatherapy in stress, anxiety, depression, sleep disorders, cognitive disorders and other disorders are described; as well as data related to its safety, adverse effects, contraindications and mechanisms of action.
Clary Sage Essential Oil and Its Effect on Human Mood and Pulse Rate: An in vivo Pilot Study.
Overall, the effects elicited by CSEO may depend on application method (inhaled/dermal) and sex (male/female); and the influence of the mode of application, which was performed showed a significant difference between sexes for the parameter of pulse rate.
Interspecies Comparison of Chemical Composition and Anxiolytic-like Effects of Lavender Oils upon Inhalation
These findings suggest that linalyl acetate (LA) works synergistically with linalool (LO) and that the presence of both LA and LO is essential for the whole oil to work as an inhaled anti-anxiety agent.


Biological activities of Lavender essential oil
There does seem to be both scientific and clinical data that support the traditional uses of lavender, but methodological and oil identification problems have severely hampered the evaluation of the therapeutic significance of much of the research on Lavandula spp.
Anxiolytic and sedative effects of extracts and essential oil from Citrus aurantium L.
The results obtained with EOP in the anxiety model, and with Eop, HF and DF in the sedation model, are in accord with the ethnopharmacological use of Citrus aurantium L., which could be useful in primary medical care, after toxicological investigation.
Evidence of the Sedative Effect of Neroli Oil, Citronellal and Phenylethyl Acetate on Mice
ABSTRACT The sedative effects of neroli oil, Citrus aurantium (L.) subsp. aurantium, citronellal and phenylethyl acetate on mice were investigated in a series of experimental procedures. Under
Aromatherapy in the Management of Psychiatric Disorders
It is concluded that aromatherapy provides a potentially effective treatment for a range of psychiatric disorders and appears to be without the adverse effects of many conventional psychotropic drugs.
Effects of the Essential Oil from Leaves of Alpinia zerumbet on Behavioral Alterations in Mice
In phytotherapy, the essential oil from the leaves of Alpinia zerumbet (Alpinia speciosa K. Schum.) (EOAZ) is used for neuropsychiatric symptoms, such as depression, stress and anxiety, and chronic
Behavioral effects of essential oil of Citrus aurantium L. inhalation in rats
The decrease in the level of emotionality of the animals observed in the two experimental models suggests a possible central action, which is in agreement with the phytochemical profile of the oil under study, since it showed the presence of limonene and mircene, components with a well-known depressant activity on the central nervous system.
Antimicrobial and antioxidant properties of some commercial essential oils
The essential oil composition of Cananga odorata, Boswellia thurifera, Cymbopogon citratus, Marjorana hortensis, Ocimum basilicum, Rosmarinus officinalis, Cinnamomum zeylanicum and Citrus limon was