Essential Guides to Method Development in Solid-phase Extraction

Abstract

Poor peak shape Wrong silica type Use type B silica Blocked frit or column void Replace frit, backflush column Silanol interactions Use amine additives, change pH, use end-capped stationary phase Excessive peak width Bad column Replace column Column overload Reduce injection volume or mass High molecular weight Normal Unresolved peaks Improve separation… (More)

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Cite this paper

@inproceedings{Wells2003EssentialGT, title={Essential Guides to Method Development in Solid-phase Extraction}, author={Martha J M Wells}, year={2003} }