Espresso reward learning, hold the dopamine: theoretical comment on Robinson et al. (2005).

@article{Berridge2005EspressoRL,
  title={Espresso reward learning, hold the dopamine: theoretical comment on Robinson et al. (2005).},
  author={Kent C. Berridge},
  journal={Behavioral neuroscience},
  year={2005},
  volume={119 1},
  pages={336-41}
}
QUESTION Is dopamine needed for reward learning? ANSWER No--at least, not in the brain of a caffeinated dopamine-deficient (DD) mutant mouse. That is the conclusion of an important paper in this issue by S. Robinson, S. M. Sandstrom, V. H. Denenberg, and R. D. Palmiter (see record 2005-01705-001). Those authors demonstrate that reward learning can proceed normally in the brains of DD mice, even though they contain no dopamine at the time of learning, if the mice are given caffeine just before… CONTINUE READING

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