Esophageal atresia: metaplasia, Barrett.

  title={Esophageal atresia: metaplasia, Barrett.},
  author={Anne Schneider and Laurent Michaud and Fr{\'e}d{\'e}ric Gottrand},
  journal={Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus},
  volume={26 4},
Barrett's esophagus is characterized by the replacement of squamous epithelium by columnar epithelium that is intestinal metaplasia-positive or -negative in the distal esophagus. Gastroesophageal reflux disease, which is frequent and prolonged in esophageal atresia, probably plays a major role in the development of Barrett's esophagus through repeated mucosal damage. Long-term acid exposure contributes to carcinogenesis in Barrett's esophagus of intestinal type, but its effect on gastric… CONTINUE READING
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