Esophageal acid sensitivity and mucosal integrity in patients with functional heartburn.

Abstract

BACKGROUND Patients with functional heartburn (FH) experience troublesome heartburn that is not related to gastroesophageal reflux. The etiology of the heartburn sensation in FH patients is unknown. In patients with reflux disease, esophageal hypersensitivity seems associated with impaired mucosal integrity. We aimed to determine esophageal sensitivity and… (More)
DOI: 10.1111/nmo.12864

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