Escherichia coli toxin gene hipA affects biofilm formation and DNA release.

@article{Zhao2013EscherichiaCT,
  title={Escherichia coli toxin gene hipA affects biofilm formation and DNA release.},
  author={Junqiao Zhao and Qian Wang and Mingji Li and Bj{\"o}rn Daniel Heijstra and Shengjun Wang and Quanfeng Liang and Qingsheng Qi},
  journal={Microbiology},
  year={2013},
  volume={159 Pt 3},
  pages={633-40}
}
Toxin-antitoxin (TA) systems in Escherichia coli may play a role in biofilm formation, but the mechanism involved remains debatable. It is not known whether the TA systems are responsible for extracellular DNA (eDNA) in biofilms. In this study, we investigated the function of the hipBA TA system in biofilm formation by Escherichia coli strain BW25113. First, the deletion of the HipBA TA system in E. coli BW25113 significantly reduced the biofilm biomass without antibiotic stress. Second… CONTINUE READING

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