Escherichia coli toxin gene hipA affects biofilm formation and DNA release.

  title={Escherichia coli toxin gene hipA affects biofilm formation and DNA release.},
  author={Junqiao Zhao and Qian Wang and Mingji Li and Bj{\"o}rn Daniel Heijstra and Shengjun Wang and Quanfeng Liang and Qingsheng Qi},
  volume={159 Pt 3},
Toxin-antitoxin (TA) systems in Escherichia coli may play a role in biofilm formation, but the mechanism involved remains debatable. It is not known whether the TA systems are responsible for extracellular DNA (eDNA) in biofilms. In this study, we investigated the function of the hipBA TA system in biofilm formation by Escherichia coli strain BW25113. First, the deletion of the HipBA TA system in E. coli BW25113 significantly reduced the biofilm biomass without antibiotic stress. Second… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 12 extracted citations


Publications referenced by this paper.
Showing 1-10 of 37 references

The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 15 Excerpts
Highly Influenced

Quorum sensing and DNA release in bacterial biofilms.

Current opinion in microbiology • 2006
View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…