Escherichia coli nusB mutations that suppress nusA1 exhibit lambda N specificity.

  title={Escherichia coli nusB mutations that suppress nusA1 exhibit lambda N specificity.},
  author={Douglas F. Ward and A Delong and Max E. Gottesman},
  journal={Journal of molecular biology},
  volume={168 1},
The bacteriophage lambda N protein regulates phage development by selectively suppressing transcription termination in its host, Escherichia coli. The E. coli nus mutants prevent N activity. To provide additional information on transcription termination, we have isolated pseudo-revertants of the nusA1 mutation that restore lambda N function. One series of pseudo-revertants lie in the E. coli nusB gene, whose product is normally required for lambda N activity. These mutations are N-specific… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-9 of 9 extracted citations

The alpha subunit of RNA polymerase and transcription antitermination.

Molecular microbiology • 1996
View 10 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…