Escherichia coli nucleoside diphosphate kinase does not act as a uracil-processing DNA repair nuclease.

@article{Bennett2004EscherichiaCN,
  title={Escherichia coli nucleoside diphosphate kinase does not act as a uracil-processing DNA repair nuclease.},
  author={Samuel E Bennett and Cheng-Yao Chen and Dale W Mosbaugh},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 17},
  pages={6391-6}
}
Escherichia coli nucleoside diphosphate kinase (Ndk) catalyzes ATP-dependent synthesis of ribo- and deoxyribonucleoside triphosphates from the cognate diphosphate precursor. Recently, the Ndk polypeptide was reported to be a multifunctional base excision repair nuclease that processed uracil residues in DNA by acting sequentially as a uracil-DNA glycosylase inhibitor protein (Ugi)-sensitive uracil-DNA glycosylase, an apurinic/apyrimidiniclyase, and a 3'-phosphodiesterase [Postel, E. H… CONTINUE READING

References

Publications referenced by this paper.

Experiments in Molecular Genetics (Cold

J. H. Miller
1972

Similar Papers

Loading similar papers…