Escherichia coli mrsC is an allele of hflB, encoding a membrane-associated ATPase and protease that is required for mRNA decay.

@article{Wang1998EscherichiaCM,
  title={Escherichia coli mrsC is an allele of hflB, encoding a membrane-associated ATPase and protease that is required for mRNA decay.},
  author={Rui Fang Wang and E B O'Hara and Mart{\'i} Aldea and Cornelia I Bargmann and H Gromley and Sidney R. Kushner},
  journal={Journal of bacteriology},
  year={1998},
  volume={180 7},
  pages={1929-38}
}
The mrsC gene of Escherichia coli is required for mRNA turnover and cell growth, and strains containing the temperature-sensitive mrsC505 allele have longer half-lives than wild-type controls for total pulse-labeled and individual mRNAs (L. L. Granger et al., J. Bacteriol. 180:1920-1928, 1998). The cloned mrsC gene contains a long open reading frame beginning at an initiator UUG codon, confirmed by N-terminal amino acid sequencing, encoding a 70,996-Da protein with a consensus ATP-binding… CONTINUE READING

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