Escherichia coli Global Gene Expression in Urine from Women with Urinary Tract Infection

@inproceedings{Hagan2010EscherichiaCG,
  title={Escherichia coli Global Gene Expression in Urine from Women with Urinary Tract Infection},
  author={Erin C. Hagan and Amanda L. Lloyd and David A. Rasko and Gary J. Faerber and Harry L. T. Mobley},
  booktitle={PLoS pathogens},
  year={2010}
}
Murine models of urinary tract infection (UTI) have provided substantial data identifying uropathogenic E. coli (UPEC) virulence factors and assessing their expression in vivo. However, it is unclear how gene expression in these animal models compares to UPEC gene expression during UTI in humans. To address this, we used a UPEC strain CFT073-specific microarray to measure global gene expression in eight E. coli isolates monitored directly from the urine of eight women presenting at a clinic… CONTINUE READING
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