Escape from adaptive conflict after duplication in an anthocyanin pathway gene

@article{Marais2008EscapeFA,
  title={Escape from adaptive conflict after duplication in an anthocyanin pathway gene},
  author={David J. Des Marais and Mark D. Rausher},
  journal={Nature},
  year={2008},
  volume={454},
  pages={762-765}
}
Gene duplications have been recognized as an important source of evolutionary innovation and adaptation since at least Haldane, and their varying fates may partly explain the vast disparity in observed genome sizes. The expected fates of most gene duplications involve primarily non-adaptive substitutions leading to either non-functionalization of one duplicate copy or subfunctionalization, neither of which yields novel function. A significant evolutionary problem is thus elucidating the… 
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