Escalation of cocaine self‐administration does not depend on altered cocaine‐induced nucleus accumbens dopamine levels

@article{Ahmed2003EscalationOC,
  title={Escalation of cocaine self‐administration does not depend on altered cocaine‐induced nucleus accumbens dopamine levels},
  author={Serge H. Ahmed and D. Lin and G. Koob and L. Parsons},
  journal={Journal of Neurochemistry},
  year={2003},
  volume={86}
}
Previous studies showed that prolonged access to cocaine or heroin self‐administration (long access, or LgA) produces an escalation in drug intake not observed with limited access to the drug (short access, or ShA). The present experiment employed in vivo microdialysis to test the role of alterations in drug pharmacokinetics and/or efficacy in increasing dopamine (DA) levels in the nucleus accumbens (NAcc) during cocaine intake escalation. In experiment 1, both ShA and LgA rats were challenged… Expand
Changes in response to a dopamine receptor antagonist in rats with escalating cocaine intake
Incentive and dopamine sensitization produced by intermittent but not long access cocaine self‐administration
Dopamine Uptake Changes Associated with Cocaine Self-Administration
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 113 REFERENCES
Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine.
Dopamine release during cocaine self-administration in rats: effect of SCH23390
...
1
2
3
4
5
...