Escalating ethanol intake is associated with altered corticostriatal BDNF expression.

Abstract

Alcoholism is a chronically relapsing condition, indicative of long-term neuronal adaptations maintaining the disease even after prolonged abstinence. Previously, we identified brain-derived neurotrophic factor (BDNF) in the dorsal striatum as the central mediator of a homeostatic mechanism which is activated by acute alcohol (ethanol) exposure and… (More)
DOI: 10.1111/j.1471-4159.2009.06073.x

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