Erythropoietin stimulates a rise in intracellular-free calcium concentration in single BFU-E derived erythroblasts at specific stages of differentiation.

@article{Miller1989ErythropoietinSA,
  title={Erythropoietin stimulates a rise in intracellular-free calcium concentration in single BFU-E derived erythroblasts at specific stages of differentiation.},
  author={Barbara Ann Miller and Joseph Y Cheung and Douglas L. Tillotson and Sharon M. Hope and Russell C Scaduto},
  journal={Blood},
  year={1989},
  volume={73 5},
  pages={1188-94}
}
Human cord blood progenitor-derived erythroblasts have recently been shown to respond to erythropoietin (Epo) or granulocyte-macrophage colony-stimulating factor (GM-CSF) with a transient increase in intracellular free calcium concentration [Cac]. However, the importance of [Cac] changes in mediating cell proliferation and/or differentiation is undefined. In the present study, the response of erythroid precursors at different stages of differentiation to Epo was examined. Erythroblasts were… CONTINUE READING