Erythropoietin production can be enhanced by normobaric oxygen breathing in healthy humans.

Erythropoietin (EPO) induces red blood cell production by activating red bone marrow progenitor cells, and is used therapeutically in chronic anemia. It is also used as an unauthorized adjunct to increase the oxygen transport capacity in the blood of athletes. Renal tissue hypoxia is the only widely accepted trigger for EPO production (1-3), even if new… (More)