Erythropoietin production by interstitial cells of hypoxic monkey kidneys

@article{Fisher1996ErythropoietinPB,
  title={Erythropoietin production by interstitial cells of hypoxic monkey kidneys},
  author={J. Fisher and S. Koury and T. Ducey and S. Mendel},
  journal={British Journal of Haematology},
  year={1996},
  volume={95}
}
  • J. Fisher, S. Koury, +1 author S. Mendel
  • Published 1996
  • Biology, Medicine
  • British Journal of Haematology
  • Previous studies which demonstrated that interstitial cells of the peritubular capillary bed of the kidneys are the site of erythropoietin (Epo) production have been performed in non‐primate species. In this study, kidneys from adult rhesus monkeys exposed to 18 h hypoxia (0.42 atm) with high serum (5685 mU/ml) and kidney (814 mU/g, includes serum EPO in the kidney) levels of Epo were compared with a kidney from a nonhypoxic normal rhesus monkey. Localization of Epo mRNA by in situ… CONTINUE READING
    92 Citations
    Erythropoietin is produced by tubular cells of the rat kidney
    • 28
    • Highly Influenced
    Erythropoietin: Physiologic and Pharmacologic Aspects
    • J. Fisher
    • Biology, Medicine
    • Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
    • 1997
    • 96
    Erythropoietin: Multiple Physiological Functions and Regulation of Biosynthesis
    • 115
    Developmental regulation of erythropoietin and erythropoiesis.
    • 158
    Developmental regulation of erythropoietin and erythropoiesis.
    • PDF
    Erythropoietin: Physiology and Pharmacology Update 2
    • J. Fisher
    • Biology, Medicine
    • Experimental biology and medicine
    • 2003
    • 499
    High glucose stimulates the expression of erythropoietin in rat glomerular epithelial cells
    • 14
    • PDF
    Cadmium and cisplatin damage erythropoietin-producing proximal renal tubular cells
    • 38
    CHAPTER 7 – Erythropoietin
    • 2

    References

    SHOWING 1-10 OF 29 REFERENCES
    Peritubular cells are the site of erythropoietin synthesis in the murine hypoxic kidney.
    • 415
    Erythropoietin gene expression in fetal and adult sheep kidney.
    • 27
    Co-localization of erythropoietin mRNA and ecto-5'-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin.
    • 312
    • Highly Influential
    Localization of cells producing erythropoietin in murine liver by in situ hybridization.
    • 120
    • Highly Influential
    • PDF
    Cellular sites of extrarenal and renal erythropoietin production in anaemic rats
    • 105
    Identification of the renal erythropoietin-producing cells using transgenic mice.
    • 357
    • Highly Influential
    Recent advances in erythropoietin research.
    • J. Fisher
    • Medicine
    • Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques
    • 1993
    • 10
    Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization.
    • 371
    • PDF
    Isolation and characterization of genomic and cDNA clones of human erythropoietin
    • 981