Erythropoietin improves left ventricular function and coronary flow in an experimental model of ischemia-reperfusion injury.

@article{Meer2004ErythropoietinIL,
  title={Erythropoietin improves left ventricular function and coronary flow in an experimental model of ischemia-reperfusion injury.},
  author={Peter van der Meer and Erik Lip{\vs}ic and Robert H. Henning and Rudolf A de Boer and Albert J Suurmeijer and Dirk Jan van Veldhuisen and Wiek H van Gilst},
  journal={European journal of heart failure},
  year={2004},
  volume={6 7},
  pages={853-9}
}
BACKGROUND Recent studies show that erythropoietin (EPO) plays a protective role in brain ischemia. In this condition, administration of EPO protects neurons from ischemic damage. Recently, it has been shown that in patients with chronic heart failure (CHF), EPO treatment improved cardiac function. In the present study we assessed the role of EPO and EPO-receptor (EPO-R) in the heart. METHODS AND RESULTS We studied the presence and functionality of the EPO-R in isolated rat hearts in the… CONTINUE READING

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